Background: Normal amniotic fluid predicts normal placental function, fetal growth and fetal well-being. Objective: To determine adverse pregnancy outcomes in borderline amniotic fluid index (AFI). Materials and Methods: Pregnant women (37-40 wks) with diagnosis of borderline AFI between December 2012 and August 2014 were identified. Antepartum, intrapartum and neonatal data were collected and compared with those of pregnant women with normal AFI. An AFI less than 8 and more than 5 cm was defined for borderline AFI. Pregnancy outcomes included Cesarean section for non-reassuring fetal heart rate, meconium stained amniotic fluid, 5-min Apgar score <7, low birth weight, umbilical cord blood pH at term and NICU admission. Results: Gestational age at delivery in pregnancies with borderline AFI was significantly lower than normal AFI. Cesarean section rate for non-reassuring fetal heart rate in women of borderline AFI was significantly higher and there was an increased incidence of birth weight less than 10PthP percentile for gestation age in borderline AFI group. Incidence of low Apgar score and low umbilical artery pH in pregnancies with borderline AFI was significantly higher than women with normal AFI. There were no significant difference in the rate of NICU admission and meconium staining in both groups. Conclusion: There are significant differences for adverse pregnancy outcomes, such as Cesarean section due to non-reassuring fetal heart rate, birth weight less than 10PthP percentile for gestation age, low 5 min Apgar score and low umbilical artery pH between pregnancies with borderline and normal AFI.

Obesity constitutes a global epidemic with increasing prevalence, associated with considerable health complications. Obese pregnant women are at increased risk for maternal and perinatal complications. This study explores the characteristics of maternal and perinatal outcomes in obese pregnant women at Dr. Soetomo General Hospital and Airlangga University Hospital, Surabaya, in 2023.This study was a descriptive and observational analysis of pregnant women with obesity who delivered at Dr. Soetomo General Hospital and Airlangga University Hospital Surabaya in 2023. The study samples were classified into three categories according to obesity classes: Class I (BMI 30-34.9), Class II (BMI 35-39.9), and Class III (BMI ≥40), and maternal and perinatal outcomes were assessed.Out of 512 subjects, the majority were from Airlangga University Hospital (75%), and 90% lived in Surabaya. 64.1% were classified as class I obesity, and 67.8% were multigravida. 53.3% delivered by cesarean section. The most common pregnancy complication was preeclampsia (23.2%), followed by gestational DM (7.6%), gestational HT (6.4%), and eclampsia (2%). There were 2.7% of subjects who experienced postpartum hemorrhage during labor, and 0.2% experienced shoulder dystocia. In terms of perinatal outcomes, 21.5% of infants had an Apgar score < 7 at 1 minute and 7.4% at 5 minutes. FGR affected 6.6% of infants, macrosomia affected 2%, congenital anomalies affected 5.1%, and the NICU admitted 15% of them. Significant differences were observed in maternal outcomes of preeclampsia, eclampsia, and mode of delivery across the three obesity classes, alongside notable differences in perinatal outcomes related to macrosomia and NICU admission (p<0.05).

Maternal, fetal and neonatal complications are correlated with hypertensive disorders during pregnancy. In this context, the maternal blood uric acid level is reported to be one of the prognostic factors in determining the prenatal outcome. Based on the existing data, the present descriptive study was performed on two groups of women with severe preeclampsia; the first group (n=53) with a uric acid level of ?6 mg/dl, was compared with the second group (n=50) with a uric acid level of <6 mg/dl. A comparison between the two groups revealed that hyperuricemia in patients with severe preeclampsia, is certainly a risk factor for several perinatal complications. Iran J Med Sci 2003; 28(4):198-199.

Background: Radiofrequency ablation (RFA) is considered as an optional treatment method in complicated monochorionic (MC) twin pregnancies. The purpose of this study is to investigate the main factors of fetal death after such treatment procedure. The study also compares the perinatal outcomes among various groups of indication and gestational age (GA) at procedure. Materials and Methods: This prospective cohort study considers 195 cases of MC multiple pregnancies including one twin with twin-twin transfusion syndrome, selective intrauterine growth restriction, sever anomaly and twin reversed arterial perfusion sequence(TRAP) which underwent selected reduction using RFA from 2016 to 2018 at Yas Hospital, Tehran, Iran. The GA at RFA categorized as 16-19+6 wks., 20-23+6 wks., and 24-28 wks. The analysis of risk factors of fetal death after RFA is based on multivariable logistic regression model. Results: The result of analysis reveals that the rate of co-twin anemia after RFA in anomaly indication was higher than the other indications significantly (p=0. 038) while according to GA categories, it is significantly lower in 20-23+6 weeks. (p=0. 016). Three independent significant factors contributing in fetal death after RFA were co-twin anemia after RFA, TRAP and anomaly indications of RFA and GA at RFA, respectively. Conclusion: The co-twin anemia after RFA was found the most contributing factor of fetal death. As the results showed that the rate of co-twin anemia after RFA is significantly low in 20-23+6 weeks of GA, such GA is suggested for RFA procedure to reduce the fetal death.